Mifepristone
نویسندگان
چکیده
منابع مشابه
Alternatives to mifepristone for early medical abortion.
OBJECTIVE To review published reports of first-trimester medical abortion regimens that do not include mifepristone. METHODS Reports listed in Pubmed and Medline on prospective and controlled trials of the efficacy of misoprostol, alone or associated with methotrexate, for first-trimester abortion were analyzed if they included more than 100 participants and were published since 1990. RESUL...
متن کاملRisks of mifepristone abortion in context.
Media attention concerning the recent update to the mifepristone labeling by the US Food and Drug Administration and Danco Laboratories has led to misconceptions about the safety of medical abortion [1]. Three women in the United States have died related to medical abortion with mifepristone (one from a ruptured ectopic pregnancy and two from infection). Approximately 360,000 women have used th...
متن کاملMifepristone (RU 486) in Cushing's syndrome.
CONTEXT Mifepristone (RU 486) blocks the action of cortisol by binding to the glucocorticoid receptor and, therefore, is of potential therapeutic value in Cushing's syndrome. However, research in endogenous hypercortisolism has been hampered by the controversy related to the use of mifepristone for inducing abortion. Currently, new studies are planned to better define the role of RU 486 in Cush...
متن کاملMifepristone (ru-486) and Its Analogues
Mifepristone (RU-486) is the first antiprogesterone drug used for the termination of early pregnancies (6 to 8 weeks pregnancies), a steroid synthesized in the laboratory. It has higher affinity for the progesterone receptor. It also has other potential applications as anticancer and glucocorticoid antagonist. It is desirable to increase its antiprogestational potency and eliminate the antigluc...
متن کاملAcute generalized exanthematous pustulosis induced by mifepristone
CASE REPORT A 26-year-old woman of Vietnamese descent presented to the emergency department with a widespread, symmetric, erythematous, and pustular eruption (Fig 1). The outbreak initially affected the waistline, and the axillary, inguinal, and inframammary folds. It then spread to involve the neck, wrists, areolae, and the antecubital and popliteal fossae (Fig 2). The pustules were superficia...
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ژورنال
عنوان ژورنال: Reactions Weekly
سال: 2021
ISSN: ['1179-2051', '0114-9954']
DOI: https://doi.org/10.1007/s40278-021-95173-1